The research project ONCODIR will identify risk factors associated with colorectal cancer and will integrate multidisciplinary research methods and technologies (including health policy analytics, artificial intelligence and decision support theories) to deliver evidence-based and personalized recommendations on colorectal cancer prevention. ONCODIR is developing a platform based on artificial intelligence and privacy principles. It will provide recommendation services based on input from citizens, clinicians and policy-makers. The project will consider factors such as lifestyle, nutrition and economics.